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ECE 498SB - Special Topics in ECE: Biophotonics

Fall 2004 Term Projects

1. Research Paper
Select a current biophotonics problem existing today
Will require extensive library text and journal search
Define problem with Professor Boppart
Develop a possible solution and describe experimental methods to prove
Prepare term paper (~25 pages)
Present 20 minute PowerPoint talk to class
List of Potential Research Papers

1.     Focus tracking schemes

2.     Laser ablation of polymers for tissue engineering

3.     Point-spread-function engineering

4.     Supercontinuum generation and uses in biology

5.     Near-infrared dye development

6.     Targeting optical probes to cancer

7.     Microscope optical designs

8.     Activate-able optical probes

9.     Single-molecule imaging

10.   Optical tomographies

11.   Cell and organelle scattering

12.   Noise issues in lasers

13.   Histology staining techniques

14.   Single cell to tissue scattering

15.   Dispersion compensation in tissue

2. Laboratory Project
Define a short-term lab-based biophotonics project
Assemble set-up and collect experimental data
Submit lab notebook with experimental approach and data
Present 20 minute PowerPoint talk to class
List of Potential Research Papers

1.     Set-up and align a titanium:sapphire laser

2.     Characterize ultrashort pulses using a FROG

3.     Investigate image visualization methods (color-scales)

4.     Determine absorption/scattering properties of tissues

5.     Construct and measure tissue phantoms

6.     Construct a microscope imaging and scanning system

7.     Perform laser ablation studies

8.     Image autofluorescence from skin

9.     Construct a goniometer for optical properties measurements

10.   Develop an acousto-optic beam scanning system

11.   Measure birefringent properties of tissue

12.   Investigate selective histological staining of tissue

13.   Generate supercontinuum from fibers

14.   Program 3-D microscope stage scanning code

15.   Construct miniature imaging fibers for catheters